Lee at al.
Neuron, 21, 1151-62, Nov 1998

* brief bath application of NMDA to hippocampal slices produces LTD
* LTD is in the CA1 region of the hippocampus
* five properties: sensitive to age, saturable, postsynaptic, reversble, doesn’t change PPF
* chemLTD and homosynaptic LTD are mutually occluding
* common expression mechanism of LTD?
* PSSA: phosphorylation site specific antibodies
* induction of chemLTD induces persistent dephosphorylation of Ser845, but not Ser831
* unexpected role of PKA in postsynaptic modulation of excitatory synaptic transmission.

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