Kameyama et al
Neuron 21, 1163-1175, Nov 1998

* NMDA-dependent LTD is associated with Ser845 dephosphorylation
* that Ser845 is normally phosphorylated by PKA
* dephophorylation of postsynaptic PKA substrate is crucial for LTD expression
* injection of cAMP analog: soaks up the PKA and prevents LTD induction!
* PKA inhibitor: produces synaptic depression that occludes homosynaptic LTD
* dephosphorylation of PKA site is one mechanism for NMDAR-dependent homosynaptic LTD expression

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